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Office of Undergraduate Research Home » 2021 Undergraduate Research Symposium Schedules

Found 1 project

Oral Presentation 4

2:45 PM to 4:15 PM
Causes and Consequences of Anterior Crossbites in Pigs
Presenter
  • Grace Ann Martin, Junior, Environmental Health
Mentors
  • Susan Herring, Orthodontics
  • Michael Baldwin, Oral Health Sciences
Session
    Session O-4E: Studies Exploring Asthma, Cranial Morphology, and Prenatal & Infant Health
  • 2:45 PM to 4:15 PM

  • Other Orthodontics mentored projects (2)
  • Other students mentored by Susan Herring (1)
  • Other students mentored by Michael Baldwin (3)
Causes and Consequences of Anterior Crossbites in Pigsclose

Pigs often have an anterior crossbite (underbite), where the maxillary incisors (upper anterior teeth) are positioned behind the mandibular incisors (lower anterior teeth) instead of in front as found in a normal dental relationship. In humans, when this condition is severe, proper feeding, speaking, and breathing can be impeded. An anterior crossbite can occur due to dental and/or skeletal malformations. Retro-inclination of the maxillary incisors or excessive pro-inclination of the mandibular incisors are dental contributors to this problem, whereas excessive growth of the mandible (lower jaw) or deficient growth of the maxilla (upper jaw) are skeletal causes. Pigs are a novel model for anterior crossbites in humans, yet it is unclear which dental or skeletal condition is the primary cause in pigs. Therefore, it is necessary to characterize this condition in pigs to translate this model to humans effectively. The purpose of this project is to determine if improper inclination of the incisors, mandibular prognathism, or maxillary retrognathism is the primary cause of anterior crossbites in pigs. A total of 150 pig skulls (120 dry skulls and 30 CT images) were included in this study. The angle of inclination of maxillary and mandibular incisors, length of the mandible, and length of the maxilla (estimated by the length of the hard palate) were measured in dry skulls using a metric protractor and ruler to the nearest degree or mm. The same measurements were taken on CT images using ImageJ software. Measurements will be compared between normal and affected pigs using t-tests and correlated to the severity of anterior crossbite using Pearson correlations. Based on the data I have acquired, I expect that the primary cause of anterior crossbites in pigs is maxillary retrognathism, also termed maxillary hypoplasia, and thus serves as a model for this specific condition in humans.


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