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Office of Undergraduate Research Home » 2020 Undergraduate Research Symposium Schedules

Found 1 project

Poster Presentation 5

1:00 PM to 1:45 PM
Evaluation of Biomechanical Properties of the Pancreatic Duct
Presenter
  • Sophia Lee Bidinger, Senior, Materials Science & Engineering UW Honors Program, Undergraduate Research Conference Travel Awardee
Mentors
  • Martin Palavecino, Surgery
  • Alex Gong, Surgery, CREST
Session
    Session T-5E: Medicine, Pathology, Pharmaceutics, Surgery
  • 1:00 PM to 1:45 PM

  • Other Surgery mentored projects (2)
Evaluation of Biomechanical Properties of the Pancreatic Ductclose

Biomechanical characterization of human tissue is of increasing importance as new technologies gain importance in modern medicine. Without haptical sensation, measurement of forces associated with surgical techniques will be the primary source of feedback in technology assisted procedures (eg. robotic surgery). An important biomechanical parameter is the suture pullout force (SPOF), the maximum safe force that could be applied to a suture before tearing the tissue.The aim of this study is to analyze suture pullout forces of the pancreatic duct. This data could be used for a wide range of applications and will be useful in understanding how biomechanical properties of the biliary tract change with age, sex, and BMI. Donated organs used in this study were tested within 72 hours of death. Cross sections of the pancreas were prepared and 4-0 sutures were looped through one side of the pancreatic duct wall. The pancreas was held in place while the suture was pulled in tension. The tensile force was measured continuously and the peak force before specimen failure was taken as the SPOF. 103 suture pullout tests were performed on pancreatic ducts from 14 donors. The overall SPOF is 2.87 N ± 1.36 N. The mean SPOF for females is 2.12 N and 3.03 N for males (p=0.019). The SPOF of pancreatic ducts from donors with BMI less than 26 averaged 3.22 N while SPOF for donors with BMI greater than 26 averaged 2.51 N (p=0.045). Donors older than 35 averaged 2.69 N while donors younger than 35 averaged 2.87 N (p=0.123). Preliminary results suggest male pancreatic ducts have a higher SPOF than female pancreatic ducts. As BMI increases, the pancreatic duct SPOF decreases. The effect of age is inconclusive at this time.


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